Hand held breast cancer imaging trialled | Oncology
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Communities Oncology Hand held breast cancer imaging trialled

Hand held breast cancer imaging trialled

Specialties

Bristol NHS Trust in the UK is trialling a new hand held breast cancer imaging tool that has been developed at the University of Bristol by Professor Alan Preece and Dr Ian Craddock. The breast-imaging device uses radio waves and therefore has no radiation risk unlike conventional mammograms. breast image scanThe team began developing and researching a prototype known as MARIA (Multistatic Array processing for Radiowave Image Acquisition) around five years ago and have received funding from a number of organisations. (Engineering and Physical Sciences Research Council (EPSRC), the trustees of the United Bristol Hospitals and the University of Bristol spin-out company, Micrima Ltd).


Dr Ian Craddock from the University's Department of Electrical and Electronic Engineering, explained: "This new imaging technique works by transmitting radio waves of a very low energy and detecting reflected signals, it then uses these signals to make a 3D image of the breast. This is basically the same as any radar system, such as the radars used for air traffic control at our airports."

Mike Shere, Associate Specialist Breast Clinician at NBT, added: "Currently women are diagnosed in three ways: firstly by a clinician then by using imaging such as mammography and ultrasound and lastly by a needle biopsy. The radar breast imaging system came to Frenchay in September this year and so far around 60 women have been examined using it. It takes less time to operate than a mammogram approximately six minutes for both breasts compared with 30-45 minutes for an MRI, and like an MRI it provides a very detailed 3D digital image. Women love it as they compare it to a mammogram and find the whole experience much more comfortable."

The radar breast imaging system is built using transmitters and receivers arranged around a ceramic cup, which the breast sits in. These transmitters view the breast from several different angles.

In the initial stages of the study the team used mammogram images to compare similar abnormalities in the new 3D image produced from the radio breast imaging system.

Professor Preece from the University's Medical Physics, said: "I started off looking at breast tumour imaging in 1990 using a hand held scanner similar to ultrasound however it did not have enough sensitivity and that's when I got to know some people in engineering and together we approached the EPSRC to help. Using this engineering knowledge we built the machine using ground penetrating radar, a similar technique to land mine detection to take four hundred quarter of a second pictures of the breast to form a 3D image. Women do not feel any sensation and it equates to the same type of radiation exposure as speaking into a mobile phone at arms length which makes it much safer."

Plans

In the near future the team plan on "testing blind"; looking at images taken by both machines and examining each independently to check whether the radio breast imaging system's 3D image picks up the same abnormalities as a mammogram would and if anything else is identified in the new image. 

They hope that if the results continue, further trials will be scheduled for the next 12 months. These trials will focus specifically on young women as these can prove the most challenging. They also hope that two new prototypes will be made for further trials in other hospitals around the country.

"This technology will ultimately only benefit the patient if it can be successfully commercialised", said Roy Johnson, CEO of Micrima Ltd, "this new invention could provide a safe, more comfortable experience for women as well as giving clinicians a better image of the breast allowing them to pick up abnormalities at an earlier stage. We particularly hope that it may work well in younger women who can pose a problem to conventional mammography."

In this stage of the process the system provides an additional picture of the breast to complement the other imaging devices available, and also has the potential to be made cheaply en-masse.

Potential Benefits

 

  • Cheap to produce
  • Portable - so suitable for a range of locations.
  • Faster scanning
  • Reduced radiation exposure
  • Provides a detailed MRI like 3D image of the breast without the need for an expensive MRI suite.
  • Suits younger women for whom mammography is sometimes unsuitable

Commercialisation

Not yet available commercially and commercialisation risks have not been disclosed. The possibility of cheap production suggests a substantial market for a device of this design.

Technical Description:

a novel breast imaging technique has been developed based upon a synthetically-focussed but real-aperture multistatic radar and is known as MARIA (Multistatic Array processing for Radiowave Image Acquisition). An ultrawideband pulse is synthesized using an Agilent 8722ES Vector Network Analyser that sweeps in frequency from 4GHz to 10GHz. The signal is transmitted from each element in an antenna array and then received by all the other elements. The large aperture and wide bandwidth theoretically allow collection of reflected and scattered signals from objects as small as 1.7mm.

Background:

Breast cancer is the most common cause of death for women aged between 35 and 59 in the EU. For various reasons the under-50s are not routinely screened. The technology has the potential to offer several advantages over existing primary screening technology, which encounters difficulties in imaging the dense tissue associated with this younger age group. MARIA promises to provide better images in such tissue, and is also relatively inexpensive, intrinsically safe, and comfortable for the patient.

The implications of this safe new technology are far-reaching, particularly as the compact size and low cost of the MARIA system will make it ideal for use in numerous alternative locations such as GP surgeries, diagnostic centres and mobile screening units.

 

 

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