Neurognostics, Inc., a Milwaukee-based medical imaging company, has signed an agreement to provide their functional MRI (fMRI) system to researchers at The Cleveland Clinic and The University of Iowa for a multi-center Huntington's disease study.

Neurognostics, Inc., a Milwaukee-based medical imaging company, has signed an agreement to provide their functional MRI (fMRI) system to researchers at The Cleveland Clinic and The University of Iowa for a multi-center Huntington's disease study.

Huntington's disease is a rare inherited central nervous system (CNS) disorder that most noticeably results in abnormal body movements and a lack of coordination, but can progressively affect mood, memory, and concentration. Individuals with a parent who has Huntington's disease have a 50 per cent chance of inheriting the disease, with a limited number of cases having no prior family history of Huntington's.

In addition to using Neurognostics' Functional Acquisition Device (fDAD™) to acquire subject data, Neurognostics has implemented three specific stimulation paradigms in collaboration with Dr. Stephen Rao and Dr. Jan Paulsen for their NIH-funded Huntington's disease study. "The paradigms that Neurognostics developed will help us test subject reasoning, attention, and timing capabilities," explains Dr. Stephen Rao, Chief Science Officer of Neurognostics and Principal-Investigator from The Cleveland Clinic. "Using these tasks, we will be able to study the cognitive function of individuals with Huntington's disease."

"We are pleased to be working with The University of Iowa and The Cleveland Clinic to study this debilitating CNS disorder," says Cathy Elsinger, Neurognostics Vice President of Research & Clinical Operations. "Neurognostics fMRI data acquisition system will provide these sites with the ability to standardize the administration of fMRI exams in the context of this research study. We hope that through the use of our system, this research will lead to breakthroughs in the evaluation and management of Huntington's disease."

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