Saline infusion sonohysterography effective for infertility workup | Radiology Articles
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Saline infusion sonohysterography effective for infertility workup

Radiology News - Radiology Articles
Saline infusion sonohysterography (SIS) effectively reveals the presence of uterine abnormalities for women undergoing infertility evaluation. NEW YORK (Reuters Health) - Saline infusion sonohysterography (SIS) effectively reveals the presence of uterine abnormalities for women undergoing infertility evaluation, experts report in the December issue of Fertility and Sterility.

Dr. Ilan Tur-Kaspa, Director of the Institute for Human Reproduction in Chicago and colleagues evaluated the efficacy of SIS in 600 women undergoing an infertility workup and 409 women with abnormal uterine bleeding.

Uterine abnormalities were found in 20% of the infertility group and in 5.5% of those with abnormal uterine bleeding.. The most common abnormality found was arcuate uterus, occurring in 15.0% of the infertility group and 6.4% of those with abnormal bleeding.

SIS revealed intracavity abnormalities in 16.2% of women in the infertility group. Abnormalities included polyps (13.0%), submucous fibroids (2.8%) and adhesions (0.3%).

Among women with abnormal uterine bleeding, SIS revealed intracavity abnormalities in 39.6%, including polyps in 29.8%, submucous fibroids in 9.0% and adhesions in 0.7%. "Saline infusion sonohysterography is an easy, safe, and well-tolerated alternative to diagnostic hysteroscopy," the team writes.

"Because it is adjunctive to transvaginal sonography, it offers the exclusive advantage of a comprehensive imaging of the uterus and the adnexa in one setting. In addition, it was shown to enhance endometrial visualization and to improve detection of intrauterine pathologies and uterine abnormalities."

"Because this technique is safe, low-cost, well-tolerated and feasible in most outpatient infertility clinics, SIS should be routinely performed in the early stage of infertility investigation," the researchers conclude.

Fertil Steril 2006;86:1731-1735.