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The MVA planimetrically decided by MDCT is methodically larger than that measured by cardiac catheterization and Doppler transthoracic echocardiogram;

Due to good correlation amid methods and regulation for the systematic bias, MDCT may facilitate steady quantification of MVS, and effective distinction amid severity grades.

Mitral Stenosis_Axial CT

The medical research was contributed by Alexander Lembcke, Tahir Durmus, Yvonne Westermann, Anja Geigenmueller, Benjamin Claus, Craig Butler and Holger Thiele from the Department of Radiology and Cardiovascular Surgery, Charité–Universitätsmedizin Berlin, Berlin, Germany; Department of Medicine, Division of Cardiology, University of Alberta, Edmonton, AB, Canada; and Department of Cardiology, Heart Center, University of Leipzig, Leipzig, Saxony, Germany. (Courtesy: American Journal of Roentgenology)

The research objective was to equate diagnostic performance of helical MDCT over cardiac catheterization, and transthoracic echocardiography, for the quantification of mitral valve stenosis (MVS).

About 28 patients with mitral valve stenosis passed through ECG-gated contrast-enhanced MDCT scan. The mitral valve area (MVA) was planimetrically established by MDCT; it was equated with Doppler TTE (transthoracic echocardiogram) through pressure half-time method. Gorlin formula was used for equation with cardiac catheterization.

Of results, planimetry of the mitral valve area with MDCT was plausible in all the cases; the MVA on MDCT was considerably larger than the same with cardiac catheterization, or transthoracic echocardiogram. (vide: Cardiology)

Correlation amid TTE & MDCT, cardiac catheterization & MDCT were good and identical to the correlation amid cardiac catheterization & TTE; the best cutoff level (concentration) for discovering moderate-severe stenosis at MDCT was an MVA of 1.70 cm2.

Conclusion: the MVA planimetrically decided by MDCT is methodically larger than that measured by cardiac catheterization and Doppler transthoracic echocardiogram; due to good correlation amid methods and regulation for the systematic bias, MDCT may facilitate steady quantification of MVS, and effective distinction amongst severity grades.