1. Brain damage found in cognitively normal people with Alzheimer's marker
(Communities/Neurology Brain CNS)

... with lower levels of a substance known as amyloid beta 42 (A-beta 42) in their cerebrospinal fluid (CSF) had reduced whole brain volumes, suggesting that Alzheimer's changes might already be damaging their ...

2. The blood-brain barrier: A misunderstood key to finding life-saving cures to brain disease
(Imported/Imported)

... Alzheimer's disease, for instance, because the BBB makes it difficult to target medication where it's needed in the brain and won't allow toxic amyloid beta proteins, believed to cause Alzheimer's, to ...

3. New way to diagnose Alzheimer's disease promises earlier treatment
(Imported/Imported)

... of AD, including atrophy (wasting) of the temporal lobe as shown on Magnetic Resonance Imaging; abnormal amyloid Beta protein concentrations in the cerebrospinal fluid; a specific pattern showing reduced ...

4. Gene variation linked to earlier onset of Alzheimer's symptoms
(Radiology News/Radiology Articles)

... as well as measuring amyloid beta 42. When PET imaging detects amyloid in the brain, patients have lower levels of amyloid-beta 42 in their cerebrospinal fluid. Goate's team found that four DNA sequence ...

5. Amyloid beta mAb shows safety and perhaps efficacy in Alzheimer's disease
(Radiology News/Radiology Articles)

Phase 2 results show that a monoclonal antibody to amyloid beta caused no adverse effects, and biomarker evidence suggested the treatment may have efficacy. Phase 2 results presented this week at the ...

6. Amyloid beta mAb shows safety and perhaps efficacy in Alzheimer's disease
(Radiology News/Radiology Articles)

Tags: [monoclonal antibody, amyloid beta, Alzheimer's disease, biomarker]  ...