1. Health Robotics Receives Overwhelming Support from its Customers for its McKesson-CytoCare Partnership
(Company News/Health Robotics)

... ago and have since utilized CytoCare to prepare patient doses from as many as 60 different drug vials of antibiotic, chemotherapy, and/or monoclonal antibody therapies for Ampicillin, Busulfan, Carboplatin, ...

2. Molecular signature may identify cisplatin-sensitive breast tumors
(Communities/Breast Mammary Gland)

... About 20 to 30 per cent of tumors, some with hormone receptors, have elevated levels of a growth-promoting protein called HER2, and those tumors are candidates for treatment with the monoclonal antibody ...

3. Researchers discover new way to reverse poor circulation and heal wounds
(Radiology News/Radiology Articles)

... various conditions. The team injected the muscle with a monoclonal antibody, which recognizes the fibronectin cryptic site, attaches to it and shuts it down. They found that vessel dilation was significantly ...

4. Recurrent brain cancer responds to new treatment
(Imported/Imported)

... studies, bevacizumab (BV), a humanized monoclonal antibody that specifically targets VEGF, in combination with irinotecan (also called CPT-11) could have a role in recurrent glioblastoma multiforme. The ...

5. PET imaging identifies aggressive kidney cancers that require surgery
(Communities/PET)

... University of Pennsylvania. In the study, the researchers used the radiolabeled monoclonal antibody G250, which was originally developed as a potential therapeutic agent by study co-author Lloyd J. Old, ...

6. Penn patient stresses value of clinical trials
(Imported/Imported)

... trial Cotara is a monoclonal antibody that targets the DNA of cancer cells and carries a radioactive isotope to them, literally destroying the cancer cells from the inside out. GBMs are complicated to ...

7. New adjuvant treatments for breast cancer prove cost-effective
(Communities/Breast Mammary Gland)

... of the anti-HER2 receptor monoclonal antibody, trastuzumab (trade name: Herceptin), is projected to improve life expectancy at a relatively low cost. Breast cancer is a major cause of cancer mortality, ...

8. Amgen drug increased bone density in trial
(Imported/Imported)

... of action than widely used bisphosphonates, such as Merck & Co's $3bn a year Fosamax, may have fewer side effects than the older drugs. Denosumab is a fully monoclonal antibody that mimics a naturally ...

9. Treatment-related AML and MDS rates 'acceptably low' after radiotherapy for NHL
(Company News/MDS Inc)

... a monoclonal antibody to CD20, which is linked to tiuxetan, which in turn chelates indium-11 for imaging and yttrium-90 for therapy. Incidence rates of AML and MDS were compiled from an analysis of data ...

10. FDA approves Avastin for breast cancer
(Communities/Breast Mammary Gland)

... shutting off its source of nourishment. The agent is a genetically engineered 'monoclonal antibody' that binds to and inhibits the activity of human vascular endothelial growth factor (VEGF), which is ...

11. Denosumab inhibits structural damage in rheumatoid arthritis patients
(Communities/Musculoskeletal )

Denosumab -- a monoclonal antibody that binds RANKL -- inhibits structural damage in rheumatoid arthritis patients, according to a report in the May issue of Arthritis & Rheumatism. Denosumab -- a ...

12. Amyloid beta mAb shows safety and perhaps efficacy in Alzheimer's disease
(Radiology News/Radiology Articles)

Phase 2 results show that a monoclonal antibody to amyloid beta caused no adverse effects, and biomarker evidence suggested the treatment may have efficacy. Phase 2 results presented this week at the ...

13. Sorafenib and bevacizumab promising for solid tumors
(Radiology News/Radiology Articles)

Combination therapy with sorafenib and bevacizumab in patients with advanced solid tumors results in enhanced antitumor activity, particularly in those with epithelial ovarian cancer. Combination therapy ...

14. Cancer drug slows multiple sclerosis
(Imported/Imported)

... a better idea of what causes MS, according to Hauser. Rituxan is a monoclonal antibody, a genetically engineered immune system protein, that attacks immune cells called B cells. "This study has taught ...

15. Rituximab reduces brain lesions, relapse rate in relapsing-remitting MS
(Imported/Imported)

... B-cell cytokine responses are often abnormal. On that basis, they tested selective CD20+ B-cell depletion using the monoclonal antibody rituximab in patients with relapsing-remitting MS. Sixty-nine patients ...

16. Peregrine Pharmaceuticals' Tumor Necrosis Therapy for the treatment of lung cancer launched in China
(Imported/Imported)

... Peregrine's proprietary Tumor Necrosis Therapy (TNT) approach links a radioactive isotope to a targeted monoclonal antibody that is designed to bind to a type of DNA that is exposed only on dead and dying ...

17. Every patient is unique: Individualized therapies for non-Hodgkin's lymphoma
(Imported/Imported)

... Most non-Hodgkin's lymphomas are from B cells. IT is a monoclonal antibody used in conjunction with radioactive medications to treat non-Hodgkin's lymphoma patients who have relapsed after treatment or ...

18. Amyloid beta mAb shows safety and perhaps efficacy in Alzheimer's disease
(Radiology News/Radiology Articles)

Tags: [monoclonal antibody, amyloid beta, Alzheimer's disease, biomarker]  ...